US residents can call their local poison control center at 1-800-222-1222. Your dose of nifedipine depends on why you need the medicine and what kind your doctor has prescribed. Review/update the Your high blood pressure could be due to an underlying condition or certain lifestyle or dietary habits. You may need to take an extended-release tablet on an empty stomach. Medically reviewed by Sanjai Sinha, MD. All rights reserved. This raises your risk of side effects from nifedipine. Your doctor may occasionally change your dose to make sure you get the best results. However, taking supplements on an empty stomach can be a big mistake, with consequences ranging from an upset stomach to limiting the supplement's effectiveness. Taking your pills with a light snack or at bedtime may help reduce the nausea. Using these drugs with nifedipine has a low risk of causing heart failure, extremely low blood pressure, or a worsening of chest pain (angina). Slow-release tablets and capsules release the medicine into your body gradually throughout the day. Nifedipine should not be used to rapidly drop blood pressure as this may be fatal and it should not be taken with grapefruit juice or grapefruit products. If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This medication is used alone or in combination with other drugs to treat high blood pressure (hypertension). This activity outlines the indications, mechanism of action, methods of . However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. It should not be used in people younger than 18 years. For pregnant women: Nifedipine is a category C pregnancy drug. Advertising revenue supports our not-for-profit mission. This can cause your body to process drugs more slowly. Some supplements and medications can also interfere with the way . You may have more severe or more frequent episodes of angina when you first start taking nifedipine or whenever your dose is changed. Part of the tablet shell may appear in your stool. health information, we will treat all of that information as protected health You should always consult your doctor or other healthcare professional before taking any medication. You may need to use an insulated bag with a cold pack to keep it cold. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Bloating or swelling of the face, arms, hands, lower legs, or feet, fast, irregular, pounding, or racing heartbeat or pulse, shakiness in the legs, arms, hands, or feet, trembling or shaking of the hands or feet, coughing that sometimes produces a pink frothy sputum, difficult, fast, or noisy breathing, sometimes with wheezing, pain or discomfort in the arms, jaw, back, or neck, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, increased urge to urinate during the night, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, sores, ulcers, or white spots on the lips or in the mouth, unsteadiness, trembling, or other problems with muscle control or coordination, vomiting of blood or material that looks like coffee grounds, redness of the face, neck, arms, and occasionally, upper chest, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, difficulty having a bowel movement (stool), excess air or gas in stomach or intestines, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, increased sensitivity of the skin to sunlight, itching, pain, redness, swelling, tenderness, or warmth on the skin, redness or other discoloration of the skin, swelling of the breasts or breast soreness in both females and males. Dizziness may increase your risk of falls. 2005-2023 Healthline Media a Red Ventures Company. Your blood pressure may need to be carefully monitored during the initial administration and titration of nifedipine. Although no "rebound" effect has been seen on discontinuation of nifedipine, it is suggested that the dose be withdrawn gradually under a doctor's supervision. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use nifedipine only for the indication prescribed. Always speak with your doctor or pharmacist about dosages that are right for you. It often rises higher during the day and falls at night when we sleep. Many patients who have high blood pressure will not notice any signs of the problem. The nifedipine extended-release tablet may contain lactose. That is, swings in blood pressure for not adhering to the regimen.. Eat a diet rich in fruits, vegetables, nuts, seeds, and legumes. Doing so can increase the level of the drug in your body and increase your risk of side effects. You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. Its also used to treat vasospastic angina (chest pain due to a spasm in arteries around the heart) or chronic stable angina (chest pain that occurs with activity or stress). Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Swallow it whole. Taking it again could be fatal (cause death). Should you be taking your blood pressure medication at bedtime rather than in the morning? Nifedipine works by causing some of your blood vessels to relax and widen. swelling of the breasts or breast soreness in both females and males. Peripheral edema (fluid retention in the lower limbs) occurs in one in ten people prescribed nifedipine. Do not worry, this is normal. Do not keep outdated medicine or medicine no longer needed. The risk is greater during initial therapy or upwards dose titration and may be more common in those already taking beta-blockers. Swallow the tablets whole. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. If you are using it to treat angina, you may take it with nitrates (nitroglycerin products) or beta-blockers. As we age, however, we may develop a blood pressure pattern called non-dipping. All rights reserved. Your doctor can tell you more. information is beneficial, we may combine your email and website usage information with Here's why some over-the-counter cough and cold medications can be dangerous for people who are living with high blood pressure. Taking medicines on an empty stomach means that you should take your pills 2 hours before you eat or 2 hours after you eat. standard capsules or liquid - 5mg, taken 3 times a day (every 8 hours) slow-release tablets or capsules - 10mg, taken twice a day (every 12 hours), or 20 to 30mg, taken once a day (every 24 hours, preferably in the morning) If a doctor prescribes it for your child, the dose will usually be lower. Swallow the extended release tablet whole. Do not stop taking nifedipine without first talking to your doctor, even if you feel fine. You may have very low blood pressure while taking this medication. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. The immediate-release capsule form of nifedipine is fast-acting and will start to have an effect within 30 minutes . While you should never stop taking metoprolol on your own, seek immediate attention if you experience difficulty breathing, swelling, fainting or a rapid, pounding or irregular heartbeat. other information we have about you. A new program developed by a research team focuses on diet, exercise, and sleep as the keys to lowering your blood pressure without using drugs. Nifedipine should not be used to rapidly drop blood pressure as this may be fatal and it should not be taken with grapefruit juice or grapefruit products. The following information includes only the average doses of this medicine. Nervousness, palpitations, cough, and nasal congestion may also be reported. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Page last reviewed: 18 February 2022 That includes 81% of people ages 55 and older. Copyright 1996-2023 Drugs.com. This dosage information is for nifedipine oral tablet. Your doctor will tell you which of these are most important for you. Severe chest pain develops in some cases (and . Other drugs may interact with nifedipine, including prescription and over-the-counter medicines, vitamins, and herbal products. Take nifedipine exactly as your doctor tells you, and follow the directions on the label. Do not crush, chew, or break a nifedipine extended-release tablet. Cold hands or feet. This can make it less effective. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. You may report side effects to the FDA at 1-800-FDA-1088. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. If you take too much: You could have dangerous levels of the drug in your body. Mayo Clinic does not endorse companies or products. There are many factors to consider, he says, such as: Your medication regimen should be personalized for you based upon a discussion with your physician, says Bhusri. Take this medication by mouth on an empty stomach, usually once daily or as directed by your doctor. Discuss the risks and benefits with your doctor. These are all extended-release tablets. Williams added, Speculation would hold that this is a good idea when the patient is known to have nocturnal hypertension but these authors suggest that it works for all comers. Medically reviewed by Carmen Fookes, BPharm. What conditions does Nifedipine ER oral treat? Dont store this medication in moist or damp areas, such as bathrooms. Available for Android and iOS devices. Headache, dizziness, nausea, flushing, constipation, leg/muscle cramps, or sexual problems may occur. You can take nifedipine at any time of day, but try to make sure it's around the same time (or times) every day. Keep these considerations in mind if your doctor prescribes nifedipine oral tablet for you. To provide you with the most relevant and helpful information, and understand which Consult your doctor for more details. Do you have large swings in your blood pressure? Do not take extra medicine to make up the missed dose. Do not crush, chew, or break a nifedipine . Does Nifedipine ER oral interact with other medications? Tips. Nifedipine oral tablet comes with several warnings. Speak to your doctor if you are . Call your doctor for medical advice about side effects. Read More. There is a problem with It works by relaxing blood vessels so blood can flow more easily. Dr. Satjit Bhusri, assistant professor of cardiology at Zucker School of Medicine at Hofstra/Northwell, also felt that it should not be a blanket recommendation for all patients. Drug interactions may change how your medications work or increase your risk for serious side effects. Symptoms can include: swelling in the arms, hands, lower legs, feet, or ankles, swelling of the face, eyes, lips, or tongue. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Qulipta, amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol. Drug information provided by: IBM Micromedex. This may cause the amount of nifedipine in your blood to be too high. You should not use this medicine if you are allergic to nifedipine, if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. For people with low blood pressure: If you have episodes of low blood pressure, taking nifedipine may make these episodes worse. Get someone else to drive you or call for an ambulance. If you take these drugs together, your doctor should monitor the level of digoxin in your body. You shouldnt take rifampin and nifedipine together. There havent been enough studies done in humans to be certain how the drug might affect the fetus. information is beneficial, we may combine your email and website usage information with Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. Your doctor may increase your dose as needed. Things to remember when you fill your prescription. Keep taking this medication even if you feel well. Mayo Clinic does not endorse companies or products. The easiest way to lookup drug information, and follow the directions on the label provider! Angina, you may have very low blood pressure: if you sick. 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